AME: Project Examples


Overview of project-examples of the AME-departments:






DFG project

  Logo CVE

Projects of the department
CVE – Cardiovascular Engineering

Projectname Short description Funding

3D-printed Membranes for Artificial Lungs

This project is part of the SPP 2014: Towards an Implantable Lung
Project number 313779459

German research foundation
Project number 347368182


Development and evaluation of minimally invasive techniques to connect an artificial lung to the heart and central vessels

This project is part of the SPP 2014: Towards an Implantable Lung
Project number 313779459

German research foundation
Project number 347325614

Alternative to conventionally used cannula of Extracorporeal Lung Assist systems

This project is part of the SPP 2014: Towards an Implantable Lung
Project number 313779459

German research foundation
Project number 346973239
ECCOR To close this temporal gap between the diagnosis of a carbon monoxide intoxication and the HBO therapy, a system for the elimination of carbon monoxide will be developed. European Union and North Rhine-Westphalia
Support Code 1606pv011
EduDerm Development and evaluation of a realistic skin, vascular and tissue model from artificial materials for the training of basic surgical skills. This research project is funded by the Program „Innovative Lehrprojekte“ of the Faculty of Medicine, RWTH Aachen
EndOxy Development of a biohybrid artificial lung Interdisciplinary Centre for Clinical Research within the faculty of Medicine at the RWTH Aachen University (T12-2)
Fontan Pro An individual adaptable fontan-prosthesis in combination with a cardiac support system is a new and innovative therapeutic option for patients, which are born with only one functioning ventricle. Federal ministry of education and research
Ghost Cells

Ghostcells are red blood cells, known as erythrocytes, with a lower intracellular hemoglobin concentration. Hemoglobin is the reddish substance inside the cells. After applying a controlled lysis, the cells are loaded with calcium and a fluorescent indicator is added to the surrounding liquid. This setup allows for the measurement of the red blood cells destruction, also called hemolysis. With those measurements, the hemolysis can be quantified spatially for the first time.

German Research Foundation
Project number STE 1680/12-1
HOC Surf

In the context of the HOC-Surf project, we investigate the applicability of the plasmaelectrolytic oxidation treatment for manufacturing cost-efficient and particular hemocompatible ceramic surfaces under the conditions of a ventricular assist device.

European Union and Land Nordrhein-Westfalen
Interventional measurement A successful replacement of a pathological heart valve requires an exact measurement of the present geometry. START-Program of the Faculty of Medicine, RWTH Aachen
Surface Structures Improving the hemocompatibility of polyurethane by means of surface structuring START-Program of the Faculty of Medicine, RWTH Aachen
OxyBench Testbed for implantable Lungs START-Program of the Faculty of Medicine, RWTH Aachen

Computational Fluid Dynamics, CFD, supports the development process of oxygenators significantly. Aim of this project is to develop the numerical model further, as well as to validate it in vitro.

German research foundation
Support code STE 1680/7-1
PLAAO Personalized LAA occluder

Federal ministry of education and research
Support code 13GW0114B

Polyvalve Polymeric Prosthetic Heart Valve for Life INTERREG Program V-A Euregio Maas-Rheine of the European Union
Grant Number 2016/98602
ProtEmbo Development and testing of a novel embolic protection device. Federal ministry of education and research
Support code 13GW0058B
PulmoStent (Part CVE) Biohybrid stent for the treatment of airway stenoses Federal Ministry of Education and Research
Support code 03VP03290

Development of a fully implantable total artificial heart that functions without any connection through the skin

European Union and Land Nordrhein-Westfalen

The CVE-Research in detail

  Logo RPE

Projects of the Department

RPE – Rehabilitation and Prevention Engineering



Development of a smart orthotic device to improve Movement capacity of patients suffering from spasticity.


Development of a robot-based rehabilitation system enabling individualized rehabilitation which can be performed autonomously by the patient.

Dyneva Examination of the effect of a dynamic flexion-orthosis on the activation of the low back muscles.
HSR-EMG Non-invasive assessment of single motor unit activity enabling diagnosis of neuromuscular disorders free of pain.
Early diagnosis of movement disorders Development of a non-invasive procedure which supports the objective and quantitative evaluation of the spontaneous motor activity of babies.
Movement Analysis of upper extremities Development of methods and procedures to analyze freely performed movements of the upper extremities.
Gait Analysis Development of novel methods to quantify the quality of gait.
Detection of limping Development of an ambulatory system allowing to analyse quality of gait

Detailed description of RPE research activities

  Logo BEE

Projects of the Department
BEE – Biophysical & Education Engineering


Blended Assessments

With support from the Stifterverband, this project figures out whether and how digital media ought to be integrated on classic testing scenarios

Problem Based Practical Courses

PBL scenarios have been implemented in university education for almost 50 years now. With small but important format changes, the concept also works for the learning of practical skills.

Electronic Assessments

After having developed this project for more than a decade, it was transferred to the department “Medien für die Lehre“. Every faculty of the RWTH Aachen University is now able and entitled to use e-assessments.

Revealing textile implants with MR

In order to avoid post-operative complications and to plan follow-up operations, a technique is developed that makes textile implants visible with MR technique.
How to detect the distribution of magnetic nanoparticles in textile implants By using a magnetic force microscope, the distribution of magnetic nanoparticles within textile implants can be measured with outstanding accuracy.

BEE-Research in detail

  Logo BEE

Projectes of the Department
BioTex - Biohybrid & Medical Textiles


The approach of the project regarding the fibre formation is the development of a bi-component spinning process that enables the spatially defined incorporation of microgels into PLA fibres.

PulmoStent Development a biohybrid stent, PulmoStent, for treatment of airway stenoses.

BioTex-Research in detail

  Logo BEE

Project of the Department
SCM – Science Management


mi-mappa A new integrative competence model of medical engineering based to be used with data mining algorithms has been conceptualized by the Department of Science Management.

Update of the trend- and innovation monitoring, in short TIM, for the medical industry in North Rhine-Westphalia


Specialized consortia developed innovative systems and solutions for cardiovascular therapy. The individual adaptation of medical devices and systems to the pathological needs of patients have been implemented in seven R&D projects.

SCM-Research in Detail


DFG project "Towards a model based control of biohybrid implant maturation"

P1 BioInterface - Functional fibrin-based hydrogels for the direction of cell/biomaterial interactions in biohybrid cardiovascular Implants
P2 Architissue - 3D-Architektur biohybrider kardiovaskulärer Implantate durch additive Fertigung
P3 TexValveModelling -
P4 ProcessModelling – Process-oriented matuaration model of biohybrid heart valves during bioreactor conditioning
P5 DurImplant – Analysis of implant behavior after bioreactor maturation in vitro
P6 ImplantMonitoring – Multimodal imaging for longitudinal in vivo monitoring of Biohybrid implants