CVE - Projects

 

Here you will find all current projects.
You will find a breakdown of the individual funding organisations in the navigation bar on the left.
You will find our finished projects also in the navigation bar on the left.

 

3DLung

This project is part of the SPP 2014: Towards an Implantable Lung.

The core technology of so-called artificial lungs are membranes that allow diffusive gas exchange between blood and gas phase similar to the native human lung. In the research project “3D-Lung”, we evaluate the next generation of oxygenator membranes based on 3D-printing technology with the potential for an implantable artificial lung by overcoming the current limitations of stand-of-the-art membranes.

 

ConnexAL

This project is part of the SPP 2014: Towards an Implantable Lung .

Lung support systems replace the lung function of patients with critical lung disease. Especially for these highly fragile patients the procedure poses a considerable risk. The aim of the project “ConnexAL” is the development and evaluation of a less invasive technique, which reduces the risk and increases the mobility for the patient. An early mobilization after surgery supports the healing process and improves the quality of life.

 

ConnLA

This project is part of the SPP 2014: Towards an Implantable Lung .

The cannulation of Extracorporeal Lung Assist (ECLA) systems is still a source of undesired complications . The project “ConnLA” aims for an alternative to conventionally used cannula such as hemodynamically optimized grafts directly connected to blood vessels.

 

DurImplant

This project is part a Sub-project P5 of PAK 961 DFG project "Towards a model based control of biohybrid implant maturation"

The aim of project “DurImplant” is the development of an in vitro methodology for the investigation of the durability of biohybrid implants with main focus on the propensity to calcification as a decisive limiting factor of the implant lifetime and function.

 

ECCOR

To close this temporal gap between the diagnosis of a carbon monoxide intoxication and the HBO therapy, the project ECCOR will develope a system for the elimination of carbon monoxide.

 

EduDerm

The project EduDerm develops and evaluates a a realistic skin, vascular and tissue model from artificial materials for the training of basic surgical skills.

 

Fontan Pro

Failing-Fontan is a present problem, which confronts cardiologists in the whole world. The Fontan-procedure enables children to survive with only one functioning ventricle. The treatment of this innate heart defect is individual for each patient and requires in some cases a cardiac support system.

 

Ghost Cells

When testing blood conducting systems regarding blood damage, flow measurements and in-vitro-blood-tests play a central role. However, a series of optical measuring methods cannot be performed with blood due to the lack of transparency. This issue is resoved by using Ghost Cells.

 

Interventional measurement

For over 20 years catheter based implantations of artificial heart valves provide an alternative to open heart surgery. The success of a catheter-based implantation depends, inter alia, on the knowledge of the measurement and form of the pathological heart valve. The implantation of an inaccurately sized heart valve can lead to severe complications. As conventional imaging-techniques show divergent measurements, a concept for a new measurement device is developed in this project.

 

MoBox

The mobilization of patients with extracorporeal lung support is the next logical development step in the field of artificial lung research. The “MoBox” project aims to close a research gap in the miniaturization of portable lung systems and is dedicated to the development of an efficiently dimensioned oxygen supply for ambulatory lung support.

 

Surface Structures

Improving the hemocompatibility of polyurethane by means of surface structuring.

 

OxyBench

“OxyBench” is an interdisciplinary research project aiming for a simulation and test platform for novel membrane oxygenators and technologies in artificial lungs for the treatment of chronic lung disease. The test methods within this project are developed to allow reproducible, preclinical long-term tests of artificial lungs.

 

OxySim

Computational Fluid Dynamics, CFD, supports the development process of oxygenators significantly. Aim of the project OxySim is to develop the numerical model further, as well as to validate it in vitro.

 

Perinatal Life Support System

The Perinatal Life Support (PLS) consortium envisions a medical device that can support the safe development of extremely preterm born infants outside the womb by preserving the innate fetal cardiorespiratory physiology ex vivo.

 

PLAAO

Atrial fibrillation leads to a five-fold increase in the stroke risk. If treatment of the atrial fibrillation fails and long-term anti-coagulation carries to much risk in a patient, the stroke risks can be reduced by implanting an occluder in the left atrial appendage (LAA). In the PLAAO project, we design a personalized LAA occluder that will improve the closure of the LAA and reduce the risk to the patient.

 

Polyvalve

Prosthetic heart valves are the sole effective treatment in patients with valvular heart disease. The project Polyvalve develops a Polymeric Prosthetic Heart Valve for Life.

 

PulmoStent

The PulmoStent is a multi-layer biohybrid Stent for the treatment of airway stenoses.

 

ReinHeart

Aim of the project ReinHeart is the development of a fully implantable total artificial heart that functions without any connection through the skin

 

Thrombosis test system: Investigation of polymeric valves in aortic position

In-vitro test system to check the thrombogenicity of Prosthetic Heart Valves

 

von Willebrand Factor

Potential of von Willebrand Factor for early detection and differentiation of shear related blood damage by blood pumps