CVE - Projects

 

Here you will find all current projects.
You will find our finished projects in the navigation bar on the left.

Our projects are supported by the German Research Foundation (DFG), the Federal Ministry of Education and Research (BMBF), the European Union and the Land Nordrhein-Westfalen, as well as the INTERREG Programme V-A Euregio Maas-Rhein of the European Union and the Medical Faculty of the RWTH Aachen University (IZKF and START).

 

3DLung

The core technology of so-called artificial lungs are membranes that allow diffusive gas exchange between blood and gas phase similar to the native human lung. In the research project “3D-Lung”, we evaluate the next generation of oxygenator membranes based on 3D-printing technology with the potential for an implantable artificial lung by overcoming the current limitations of stand-of-the-art membranes.
Funded by the DFG. This project is part of the SPP 2014: Towards an Implantable Lung.
Aim of the SPP is to enable research to support the development of long-term implantable lung assist systems.

 

ConnexAL

Lung support systems replace the lung function of patients with critical lung disease. Especially for these highly fragile patients the procedure poses a considerable risk. The aim of the project “ConnexAL” is the development and evaluation of a less invasive technique, which reduces the risk and increases the mobility for the patient. An early mobilization after surgery supports the healing process and improves the quality of life.
Funded by the DFG. This project is part of the SPP 2014: Towards an Implantable Lung.
Aim of the SPP is to enable research to support the development of long-term implantable lung assist systems.

 

ConnLA

The cannulation of Extracorporeal Lung Assist (ECLA) systems is still a source of undesired complications . The project “ConnLA” aims for an alternative to conventionally used cannula such as hemodynamically optimized grafts directly connected to blood vessels.
Funded by the DFG. This project is part of the SPP 2014: Towards an Implantable Lung.
Aim of the SPP is to enable research to support the development of long-term implantable lung assist systems.

 

DurImplant

The aim of project “DurImplant” is the development of an in vitro methodology for the investigation of the durability of biohybrid implants with main focus on the propensity to calcification as a decisive limiting factor of the implant lifetime and function.
Funded by the DFG. This project is part a Sub-project P5 of PAK 961 DFG project "Towards a model based control of biohybrid implant maturation" .

 

ECCOR

To close this temporal gap between the diagnosis of a carbon monoxide intoxication and the HBO therapy, the project ECCOR will develope a system for the elimination of carbon monoxide.
Funded by European Union and North Rhine-Westphalia .

 

EduDerm

The project EduDerm develops and evaluates a a realistic skin, vascular and tissue model from artificial materials for the training of basic surgical skills.
Funded by the Program „Innovative Lehrprojekte“ of the Faculty of Medicine, RWTH Aachen.

 

Fontan Pro

Failing-Fontan is a present problem, which confronts cardiologists in the whole world. The Fontan-procedure enables children to survive with only one functioning ventricle. The treatment of this innate heart defect is individual for each patient and requires in some cases a cardiac support system.
Funded by the BMBF.

 

Fluorescent Ghosts

The minimization of hemolysis is a core objective of the development of blood-bearing medical devices such as blood pumps or heart valves.
The PIV measurement allows for a spatially resolved flow analysis and can reveal possible sources of hemolysis. In standard-compliant in-vitro experiments, blood is used as the test medium. Here, however, only the blood damage of the entire system can be quantified. These two aspects can be combined with the help of so-called ghost cells.
Within the scope of the Ghostcell follow-up project, the Fluorescent Hemolysis Detection with PIV will be combined, optimized and validated in-vitro to finally enable the spatially resolved hemolysis detection in blood-bearing medical devices.

 

Interventional measurement

For over 20 years catheter based implantations of artificial heart valves provide an alternative to open heart surgery. The success of a catheter-based implantation depends, inter alia, on the knowledge of the measurement and form of the pathological heart valve. The implantation of an inaccurately sized heart valve can lead to severe complications. As conventional imaging-techniques show divergent measurements, a concept for a new measurement device is developed in this project.
Funded by the START-Program of the Faculty of Medicine, RWTH Aachen.

 

MoBox

The mobilization of patients with extracorporeal lung support is the next logical development step in the field of artificial lung research. The “MoBox” project aims to close a research gap in the miniaturization of portable lung systems and is dedicated to the development of an efficiently dimensioned oxygen supply for ambulatory lung support.
Funded by the
START-Program of the Faculty of Medicine, RWTH Aachen.

 

Surface Structures

Improving the hemocompatibility of polyurethane by means of surface structuring.
Funded by the START-Program of the Faculty of Medicine, RWTH Aachen.

 

OxyBench

“OxyBench” is an interdisciplinary research project aiming for a simulation and test platform for novel membrane oxygenators and technologies in artificial lungs for the treatment of chronic lung disease. The test methods within this project are developed to allow reproducible, preclinical long-term tests of artificial lungs.
Funded by the
START-Program of the Faculty of Medicine, RWTH Aachen.

 

OxySim 2

Aim of the OxySim 2 project is to establish a method for a quantitative prediction of gas transfer in oxygenators.
Funded by the DFG.

 

Oxytestfluid

In the project Oxytestfluid, investigations on blood substitutes are performed and a novel test method for reproducible, preclinical performance testing of artificial lungs is developed.
Funded by the START-Program of the Faculty of Medicine, RWTH Aachen.

  Logo of the project

Perinatal Life Support System

The Perinatal Life Support (PLS) consortium envisions a medical device that can support the safe development of extremely preterm born infants outside the womb by preserving the innate fetal cardiorespiratory physiology ex vivo.
Funded by Horizon 2020.

 

Polyvalve

Prosthetic heart valves are the sole effective treatment in patients with valvular heart disease. The project Polyvalve develops a Polymeric Prosthetic Heart Valve for Life.
Funded by the INTERREG Program V-A Euregio Maas-Rheine of the European Union.

 

PulmoStent

The PulmoStent is a multi-layer biohybrid Stent for the treatment of airway stenoses.
Funded by the BMBF.

 

ReinHeart

Aim of the project ReinHeart is the development of a fully implantable total artificial heart that functions without any connection through the skin.
Funded by the European Union and Land Nordrhein-Westfalen .

 

Thrombosis test system: Investigation of polymeric valves in aortic position

In-vitro test system to check the thrombogenicity of Prosthetic Heart Valves

 

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