CVE - Projects


Here you will find all current projects.
You will find our finished projects in the navigation bar on the left.

Our projects are supported by the German Research Foundation (DFG), the Federal Ministry of Education and Research (BMBF), the European Union and the Land Nordrhein-Westfalen, as well as the INTERREG Programme V-A Euregio Maas-Rhein of the European Union and the Medical Faculty of the RWTH Aachen University (IZKF and START).



The aim of this research project is to develop a prototype of an implantable artificial lung based on 3D-membranes. Therefore, we will develop a method to integrate 3D-membranes into physiological design volumes and to optimize flow distribution inside the device through local membrane geometry variations.



The aim of project “DurImplant” is the development of an in vitro methodology for the investigation of the durability of biohybrid implants with main focus on the propensity to calcification as a decisive limiting factor of the implant lifetime and function.
Funded by the DFG. This project is part a Sub-project P5 of PAK 961 DFG project "Towards a model based control of biohybrid implant maturation" .


Fluorescent Ghosts

The minimization of hemolysis is a core objective of the development of blood-bearing medical devices such as blood pumps or heart valves.
The PIV measurement allows for a spatially resolved flow analysis and can reveal possible sources of hemolysis. In standard-compliant in-vitro experiments, blood is used as the test medium. Here, however, only the blood damage of the entire system can be quantified. These two aspects can be combined with the help of so-called ghost cells.
Within the scope of the Ghostcell follow-up project, the Fluorescent Hemolysis Detection with PIV will be combined, optimized and validated in-vitro to finally enable the spatially resolved hemolysis detection in blood-bearing medical devices.



Better understanding of mechanically induced hemolysis using experimental and numerical methods to improve the design of current blood-carrying medical devices
Funded by the DFG.


OxySim 2

Aim of the OxySim 2 project is to establish a method for a quantitative prediction of gas transfer in oxygenators.
Funded by the DFG.



In the project Oxytestfluid, investigations on blood substitutes are performed and a novel test method for reproducible, preclinical performance testing of artificial lungs is developed.
Funded by the START-Program of the Faculty of Medicine, RWTH Aachen.

  Logo of the project

Perinatal Life Support System

The Perinatal Life Support (PLS) consortium envisions a medical device that can support the safe development of extremely preterm born infants outside the womb by preserving the innate fetal cardiorespiratory physiology ex vivo.
Funded by Horizon 2020.



Development of a medical device for combined pulmonary and renal support therapy.
Funded by the DFG. This project is part of the SPP 2014: Towards the implantable lung.
The goal of the SPP is to support research leading to the development of a long-term implantable lung support system.



Thrombogenicity Reduction by Means of Surface Structures – A Combined In-silico and In-vitro Study.
Funded by the DFG and the ANR (France).


Thrombosis test system: Investigation of polymeric valves in aortic position

In-vitro test system to check the thrombogenicity of Prosthetic Heart Valves



in-vitro approach to assess the thrombotic potential in blood-recirculating devices to facilitate research and development, regulatory processes, and to better understand the process of thrombosis.



Flow study in femoro-femoral VA ECMO and the analysis of afterload elevation and Harlequin syndrome using virtual models.


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