Interventional measurement

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Anna Grünwald

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+49 241 80 85873

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Background

The number of minimal-invasive implanted transcatheter heart valves as a trancatheter aortic valve implantation (TAVI) in high risk patients increases steadily worldwide [1]. Although interventional transcatheter interventions are performed regularly these days, disastrous complications can occur during and after the TAVI. Reasons for these complications are, inter alia, the choice of an incorrect prosthesis size and the resulting inaccurate positioning. The exact identification of the dimension and deformation of the pathological anatomy is necessary for the choice of a suitable prosthesis size. The choice is usually made by means of imaging techniques. These show not only limited visual recognition and therefore high limitations, but also cause, depending on the method, high radiation exposure (e.g. CT). Furthermore measuring balloon catheter can be used. These can only be dilated on the maximal volume. Consequently important anatomic structures can be injured in the case of an incorrect size choice.

Aim of Project

The aim of this project is the development of a new device, which allows the measurement of the native heart valve with a low risk of injury.

Through this device it will be possible for the attending physician to see size information, which are necessary for further treatment. Furthermore the new instrument provides the opportunity, to give information about the mechanical properties of the ring structure of the aortic valve. By means of these information fitting prostheses can be chosen and the default risk (migration, embolization, closure of the coronary arteries) can be decreased.

Forecast

The risk of the implantation of an incorrect dimensioned prosthesis can be reduced by the use of the measuring device and by this, increase the safety of a transcatheter procedure on the heart significantly. The option of a TAVI could consequently be expanded to a larger respectively different patient group, which is currently excluded due to the above mentioned reasons.

Cooperation Partner Klinik für Kardiologie, Interventionelle Kardiologie, UK Aachen
Founded by This research project is supported by the START-Program of the Faculty of Medicine, RWTH Aachen